College of Engineering Unit:
Parkinson's is a disease that affects millions of people worldwide, and often requires medication to manage the symptoms. Specific dosage regimens are highly tailored to each individual and can vary daily, but the testing required to select a dosage is invasive, costly, and takes ages to get results. Our project addresses this problem with a point-of-care diagnostic device. The device consists of a porous microneedle patch to sample the interstitial fluid (ISF) of a patient, which is applied through an applicator device to stabilize the needles and applies pressure to the patch. The microneedle patch is inserted into the skin, drawing up the ISF sample, which undergoes a colorimetric reaction in an attached assay pad. The intensity of this colorimetric reaction is dependent on the concentration of the drug in the sample and is imaged by a camera within the imaging apparatus, which has a microcontroller attached capable of analyzing the image and determining the concentration of the drug present within the patient’s sample. With this device, Parkinson's patients have increased access to minimally invasive therapeutic monitoring, and for a fraction of the cost.Micronee
| Attachment | Size |
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 2023.expoposter.bioe08.pdf | 3.36 MB |